An adhesive that can stimulate muscles to stretch and contract has been developed - and it has the potential to prevent and enable recovery from muscle atrophy. Muscles can become weak and waste away due to a lack of exercise, such as when a limb is immobilized in a cast, or gradually as people a
December 30, 2022
Muscles can become weak and waste away due to a lack of exercise, such as when a limb is immobilized in a cast, or gradually as people age. This condition, known as muscle atrophy, can also occur as a result of neurological disorders like ALS and MS, or as a response to certain diseases including cancer and diabetes.
In this way, the device is aligned with the natural axis of muscle movement, transmitting the mechanical force generated by SMA deep into the muscle. Mooney’s group is advancing MAGENTA, which stands for “mechanically active gel-elastomer-nitinol tissue adhesive,” as one of several Tough Gel Adhesives with functionalities tailored to various regenerative applications across multiple tissues.
“There is a good chance that distinct soft robotic approaches with their unique effects on muscle tissue could open up disease or injury-specific mechano-therapeutic avenues,” said Mooney.
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