A new study suggests that depression after traumatic brain injury may not be the same as depression related to other causes, according to researchers from Brigham and Women’s Hospital.
The study of 273 people found that brain circuits associated with depression were different between people with traumatic brain injury and those without TBI.
“If we’re right, it means that we should be treating depression after TBI like a distinct disease,” Siddiqi added. “Many clinicians have suspected that this is a clinically distinct disorder with a unique pattern of symptoms and unique treatment response, including poor response to conventional antidepressants — but until now, we didn’t have clear physiological evidence to prove this.”
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