Science, Space and Technology News 2023
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In the new study, Dr. Lyssenko’s team addressed how cholesterol metabolism and inflammation may manipulate ABCA7 levels in human brain cells and thus affect Alzheimer’s disease pathogenesis. In one set of experiments, the researchers depleted cholesterol in different neural cell lines, such as microglia, astrocytes, and neurons, and then treated the cells with rosuvastatin, a medication that suppresses cholesterol synthesis.
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