A strain of MRSA that emerged in pigs and is highly antibiotic-resistant can spread to humans. According to recent research, pig farming's extensive use of antibiotics has likely contributed to the emergence of a highly antibiotic-resistant strain of the superbug MRSA, or methicillin-resistant Stap
A highly antibiotic-resistant form of the superbug MRSA was discovered in a recent investigation.According to recent research, pig farming’s extensive use of antibiotics has likely contributed to the emergence of a highly antibiotic-resistant strain of the superbug MRSA, or methicillin-resistant Staphylococcus aureus, in livestock during the last 50 years.
Intensification of farming, combined with high levels of antibiotic use in livestock, has led to particular concerns about livestock as reservoirs of antibiotic-resistant human infections. Credit: Mark Holmes She added: “We found that the antibiotic resistance in this livestock-associated MRSA is extremely stable – it has persisted over several decades, and also as the bacteria has spread across different livestock species.”
While livestock-associated CC398 is found across a broad range of livestock species, it is most commonly associated with pigs. Its rise has been particularly evident in Danish pig farms where the proportion of MRSA-positive herds has increased from less than 5% in 2008 to 90% in 2018. MRSA doesn’t cause disease in pigs.
The researchers reconstructed the evolutionary history of two particular mobile genetic elements called Tn916 and SCCmec that confer antibiotic resistance in MRSA, and found they have persisted in a stable way in CC398 in pigs over decades. They also persist when CC398 jumps to humans – carrying with them high levels of resistance to antibiotics commonly used in farming.
Intensification of farming, combined with high levels of antibiotic use in livestock, has led to particular concerns about livestock as reservoirs of antibiotic-resistant human infections.
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