Hepatitis B: a new weapon against an old enemy - Nature Medicine

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Hepatitis B: a new weapon against an old enemy - Nature Medicine
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In our recent News and Views, T. Jake Liang from NIDDKgov discusses new strategies based on nucleic acid technologies to treat chronic hepatitis B WorldHepatitisDay

Chronic infection with hepatitis B virus afflicts more than 250 million people worldwide.

Effective vaccines and treatments that potently suppress viral levels and reduce liver inflammation have been available for over 20 years, but infection with HBV continues to exact a heavy public-health toll. The goal of a ‘cure’ for chronic infection with HBV remains elusive. At present, nucleoside analogs and interferon-α are the only approved therapies, and they rarely cure the infection

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