Recent patents relating to compositions and methods for targeted editing of nucleic acids
Strategies, systems, reagents, methods and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject; for example, within the human genome. In one embodiment, fusion proteins comprise a Gam protein, a nucleic acid programmable DNA binding protein and a cytidine deaminase.
The base editor can edit bases in DNA, deaminates cytosine into uracil, and has high editing efficiency even if cytosine is positioned at a GpC site or is in a hypermethylated state.Adenosine deaminases that are capable of deaminating adenosine in DNA. Also, fusion proteins comprising a Cas9 domain and adenosine deaminases that deaminate adenosine in DNA.
Indonesia Berita Terbaru, Indonesia Berita utama
Similar News:Anda juga dapat membaca berita serupa dengan ini yang kami kumpulkan dari sumber berita lain.
UK, BioNTech test mRNA against cancer - Nature BiotechnologyIn Brief: NHSEngland and GenomicsEngland partner with BioNTech_Group to fast-track up to 10,000 patients into clinical trials of mRNA immunotherapies to treat cancer
Baca lebih lajut »
Deconvolution of clinical variance in CAR-T cell pharmacology and response - Nature BiotechnologyA model of T cell differentiation control deconvolutes biological mechanisms underlying clinical variance.
Baca lebih lajut »
Interstrand crosslinking of homologous repair template DNA enhances gene editing in human cells - Nature BiotechnologyInterstrand crosslinking of homologous repair template DNA enhances gene editing in human cells - mcdbucsb
Baca lebih lajut »
High-throughput, targeted MHC class I immunopeptidomics using a functional genetics screening platform - Nature BiotechnologyPeptides that bind MHC class I are readily identified with a programmable, high-throughput method.
Baca lebih lajut »
Audio long read: How your first brush with COVID warps your immunityListen to an audio version of a recent Nature feature.
Baca lebih lajut »