A Bad Night's Sleep Could Weaken Your Response to Vaccines

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A Bad Night's Sleep Could Weaken Your Response to Vaccines
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Research found a link between little sleep and a poorer response to vaccines, though more work is needed to understand the connection.

finding that intentionally sleep-deprived young and healthy men went on to have a reduced immune response to the flu vaccine. During the first year of the pandemic, they became interested in the topic again, reached out to other scientists, and started work on a meta-analysis of existingearlier studies, including several experimental trials.

sleep data, though that can be explained by people generally being bad at knowing how much sleep they get. But the studies that relied on objective sleep measures only looked at people 60 and younger, meaning there’s no clear data on older people. The research also only tracked people’s immune responses following immunization to influenza and the hepatitis A and B viruses.

Despite the gender gap in their findings, the authors believe that sleep deprivation can still affect women’s response to vaccination. They argue that past studies might have failed to confirm this link because they didn’t account for other factors that could affect the results, namely fluctuating hormone levels caused by the menstrual cycle, birth control, or menopause.

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