New research proves dogs, even tiny ones, are descended from wolves.
. An analysis of 1,431 genome sequences spanning 13 species of both ancestral and modern canids revealed a variant, or gene mutation, within the antisense that interacts with the IGF-1 gene. This was “really the key that unlocked everything,” Ostrander said.
These alleles have conferred “morphological plasticity” to modern dogs; because both alleles are circulating within the global dog population, people can selectively breed dogs of widely different sizes. For example, there are three sizes of schnauzers: toy, miniature and standard. The toy and miniature schnauzers analyzed in the study contained the small allele, while the giant schnauzers contained the large allele.
The study suggests this large allele most likely emerged in wolves more than 53,000 years ago, likely due to natural selection. These wolves lived during the Pleistocene, also known as “t.” Lower temperatures likely caused this allele to become a fixed feature of northern wolves, while the small allele persisted in wolves living in southern, warmer regions.
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