ICU patients on probiotics were more likely to develop a lactobacillus infection than those not on probiotics, a new study found. But researchers emphasize that the risk of infection they found in no way means that probiotics are dangerous for everyone.
In an intensive care unit at Boston Children's Hospital, Dr. Greg Priebe was treating a teenager whose lungs had failed. To make matters worse, the patient spiked a fever from an infection brewing in his bloodstream: a type of bacteria called lactobacillus, commonly found in probiotic capsules and foods like yogurt.
"Those two cases kind of made me start thinking that maybe there is a problem there, because that patient was also taking a probiotic containing lactobacillus," Priebe says. "And over about a five-and-a-half year period, we noticed that there were six patients who had been receiving probiotics in the ICU who had a positive blood culture — a blood stream infection — with this particular bacteria called lactobacillus," he says."And so that seemed like it was something that was worth looking into a little bit further."
They used state-of-the-art technology called whole genome sequencing that can compare all the"bases" — the As, Cs, Ts and Gs that are like the letters in the book of your DNA. It was ground-breaking work to nail down the DNA match so definitively using the latest tools, says Christina Merakou, a post-doctoral fellow at Children's.
Gregory Priebe, Christina Merakou and Thomas Sandora in one of the intensive care rooms at Boston Children’s Hospital
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