Recurrent UTIs could one day be prevented with a vaccine instead of antibiotics if promising results in mice and rabbits are replicated in clinical trials
at Duke University in North Carolina and their colleagues have developed a vaccine for preventing UTIs.
It has been formulated as a tablet that dissolves under the tongue. This mode of vaccine delivery can elicit immune responses in the urinary tract due to similarities between the mucous membranes lining the mouth and urinary tract.The tablet can be self-administered and is stable at room temperature, making it easy to store, transport and use. “Eliminating the cold-chain requirement has the potential to lower costs of vaccine delivery,” says Kelly.
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