Clinical study on nasopharyngeal cancer with an unexpected result. Patients with nasopharyngeal cancer are often treated with drugs that activate their immune system against the tumor. Scientists feared that vaccination against COVID-19 could reduce the success of cancer treatment or cause severe
are a common condition in countries in Southeast Asia. However, concerns that the therapy might interact unfavorably with Covid vaccination appear to be unfounded. Credit: Y.J. Hua / Sun Yat-sen University Cancer CenterPatients with nasopharyngeal cancer are often treated with drugs that activate their immune system against the tumor. Scientists feared that vaccination againstcould reduce the success of cancer treatment or cause severe side effects—until now.
Many cancer cells are capable of subverting the body’s immune response. They do this by pushing a kind of button on the immune cells, the PD-1 receptor. In this way, they effectively shut down these endogenous defense forces. Drugs can be used to block PD-1 receptors. This enables the immune system to fight the tumor more effectively.
Together with cooperation partners from the People’s Republic of China, the bioinformatician has now investigated whether this concern is justified. More than 1,500 patients treated in 23 hospitals from all over China participated in the analysis. Such multi-center studies are considered to be particularly informative because the participants are very diverse and, moreover, the results are not distorted by regional characteristics.
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