Scientists have found that both a sedentary lifestyle and shorter white blood cell telomeres may be linked to greater risk of developing dementia.
New insights into the medical mysteries behind dementia have been revealed this week, with two studies identifying drivers of the brain-degenerating condition.shows that the shortening of little caps on the end of chromosomes may be linked to increased dementia risk. Another,on September 12, reveals that spending more time sedentary, such as sitting down, may also increase the risk.
According to the paper, data from UK Biobank—a large biomedical database—reveals that of patients between the ages of 37 and 73, those with shorter telomeres in their leucocytes were 14 percent more likely to be diagnosed with dementia than those with the longest telomeres, and 28 percent more likely to be diagnosed with Alzheimer's disease."We found that LTL [leucocyte telomere length] acts as an aging biomarker associated with the risk of dementia," the authors wrote.
"The link between sedentary behavior was nonlinear, so that at lower amounts of sitting time, there was no significant increase in risk," study author David Raichlen, professor of biological sciences and anthropology at the USC Dornsife College of Letters, Arts and Sciences, told."After about 10 hours per day of sedentary behavior, risks increased significantly.
They also found that even if this sedentary time is broken up by periods of activity, it's only the total time spent sitting that appears to have an impact on dementia risk.
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