'Back-to-school' season means buying pens, figuring out the bus route, and ... earaches. Cutting corners with antibiotics, however, can accelerate resistance. Today, researchers report developing a single-use nanoscale system that's unlikely to generate resistance. Using a compound similar to bleach in test animals, they show it can kill off a bacterium that causes ear infections, and it could someday be easily applied as a gel.
"Back-to-school" season means buying pens and paper, figuring out the new bus route, and … earaches. Doctors typically treat these infections with antibiotics, but children don't always complete the full course, accelerating resistance to these medications. Today, researchers report developing a single-use nanoscale system that's unlikely to generate resistance.
"We initially conceived of this idea by looking at the household cleaner bleach. Even though it has been used since the 19century, bacteria do not appear to have developed any widespread resistance to this cleaner," says Rong Yang, Ph.D., the project's principal investigator. After realizing that the active ingredient in the household cleaner could circumvent antibiotic resistance, the researchers, who are at Cornell University, decided to tackle a nearly universal childhood scourge: acute ear infections. These infections affect more than 95% of children in the U.S., and treatment typically requires taking antibiotics for five to 10 days.
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