This Scientist-Entrepreneur Is Brewing Prescription Drug Ingredients Like They Were Beer

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This Scientist-Entrepreneur Is Brewing Prescription Drug Ingredients Like They Were Beer
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Backed by $123 million in venture investments, Christina Smolke’s company Anthiea just completed its first scaled production of a key drug ingredient.

Backed by $120 million in venture funding, Stanford professor Christina Smolke’s company Anthiea just completed its first scaled production of a key drug ingredient.very year, thousands of people around the globe use a bioengineering process where they take sugar, feed it to a carefully-selected strain of yeast and a few days later extract a product that’s then sold and enjoyed by millions. Most people call this brewing beer.

According to an August survey from the American Society of Health System Pharmacists, shortages of essential medicines areone-third of hospital pharmacists to ration, delay or cancel needed medical interventions. The other two-thirds said they’re managing these shortages strategically, but that there’s still an impact on patient care because the price of some essential medications have increased.

“We’re producing ingredients where there are supply chains with recurring inefficiencies,” says Christina Smolke, cofounder and CEO of Antheia. “We’re looking long-term at where things are becoming unsustainable.” To make large quantities of drug ingredients, Antheia’s researchers first had to engineer the yeast itself. That process involved taking genes from the plants from which the drug ingredients are harvested and adding them to the yeast, along with genes from over 20 other organisms to make the process more efficient.

That said, Helal notes that by focusing on pharmaceutical companies delivering essential medicines, “there’s definitely a viable path to commercial success” if the company’s able to deliver at scale.

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