The Side Effects of Million-Dollar Drugs

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The Side Effects of Million-Dollar Drugs
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Heard on the Street: Gene therapies will bring hope for patients and opportunity for investors—as long as someone is willing to pay for them

It’s only a matter of time until the first million-dollar drug arrives in a deeply dysfunctional health-care system. With the new drugs come painful questions: Who is stuck with the bill, do they have the cash to pay it and how can they avoid the obligation?

The age of gene therapy promises a wave of life-changing and life-saving medicines. Some have been approved, like Luxturna from Spark Therapeutics, which treats a hereditary disease that causes blindness and affects roughly 2,000 patients in the U.S. Roche agreed to buy...

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