The Chaotic Monkeypox Vaccine Pipeline Is Leaving Everyone Short

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The Chaotic Monkeypox Vaccine Pipeline Is Leaving Everyone Short
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A Danish company that’s the sole producer of the only approved vaccine has sold nearly all its supplies to the US, and it won’t be making new doses until 2023.

But bizarrely, even though it owns most of the current stock, the US hasn’t secured a consistent supply of usable vaccines. The country has been stockpiling doses for years—to protect against smallpox, which it also works against, in the event of a bioterror attack—and has bought close toover the past two decades. However, the vast majority of the usable doses it ordered in the past expired sitting in freezers and were never replaced, despite the US having many more on order.

For the rest of the order, the bulk form of the vaccine needed to be processed into usable doses at a new fill-and-finish plant that Bavarian Nordic had completed in 2021, but the FDA hadn’t at the time approved that facility for supplying materials to the US. This meant that on May 23, over 200,000 doses that could have gone toward fulfilling the US’ request from 2020 were delivered instead to European countries while the FDA finished up its inspection.

The FDA has now finally signed off the facility, meaning 786,000 more doses have since been shipped to the US. Up to the middle of July, the US also put in new orders for about 5 million more usable doses, but because of its tardiness earlier in the summer, by this point other countries had already snapped up the existing supply of ready-to-use vaccines—meaning that these newly ordered usable doses can be delivered only in 2023.

from July 15, Bavarian Nordic said it expected to deliver nearly 7 million doses to the US in 2022 and 2023.

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