Japan's biggest drugmaker, Takeda Pharmaceutical Co Ltd, said long-term dat...
- Japan’s biggest drugmaker, Takeda Pharmaceutical Co Ltd, said long-term data show better outcomes for its Alunbrig drug in certain lung cancer patients compared to an existing treatment.
Oncology is a pillar for Takeda as it refocuses on core businesses following last year’s $59 billion takeover of Britain’s Shire. The announcement followed a week of investor conferences at home and in the United States intended to show that its drug pipeline is robust enough to fuel continued growth.
“This is a profoundly exciting study,” said Rachael Brake, Takeda’s global program leader in oncology. “The benefit in the overall study population, as well as in patients with baseline brain metastises, is associated with an improved quality of life relative to crizotinib.” Alunbrig is a tyrosine kinase inhibitor designed to target and inhibit the ALK fusion protein in non-small cell lung cancer. It received accelerated approval from the U.S. Food and Drug Administration in April 2017 for certain cancer patients who had progressed on or were intolerant to crizotinib, a similar class of drug.Non-small cell lung cancer is the most common form among the estimated 1.
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