Side effects from the Pfizer and Moderna vaccines in the United States have largely been mild and short-lived, a large new study of the first 6 months of vaccinations shows.
Injection site pain, fatigue orIn about one third of the reports, patients said they were unable to work or do normal activities after the second dose, while similar reports after the first dose came from 12% of patients.Fewer than 1% of participants needed medical care after dose 1 or 2 of the vaccine.
Women were more likely than men to report problems after vaccination, and young people were more likely than those over 65 to experience side effects.Study authors say these effects were similar to what Pfizer and Moderna reported in clinical trials before they were granted FDA authorization."The safety monitoring of the mRNA COVID-19 vaccines stands out as the most comprehensive of any vaccine in U.S. history.
Krantz and Phillips point out in a separate commentary that the v-safe reports of reactions are consistent with those reported from clinical trials and a real-life study in the United Kingdom. "[A]lthough approximately one in 1000 individuals vaccinated may have an adverse effect, most of these are nonserious,” Phillips said in a press release.