The brains of adolescents who were assessed after the COVID pandemic shutdowns ended appeared several years older than those of teens who were assessed before the pandemic. Until now, such accelerated changes in “brain age” have only been seen in children experiencing chronic adversity, such as negl
Pandemic-related stressors have physically altered adolescents’ brains, making their brain structures appear several years older than the brains of comparable peers before the pandemic. This is according to a new study from Stanford University that was published on December 1, 2022, in the journalIn 2020 alone, reports of anxiety and depression in adults rose by more than 25 percent compared to previous years.
By comparing MRI brain scans from a cohort of 163 children taken before and during the pandemic, Gotlib’s study showed that this developmental process sped up in adolescents as they experienced the COVID-19 lockdowns. Until now, he says, these sorts of accelerated changes in “brain age” have appeared only in children who have experienced chronic adversity, whether from violence, neglect, family dysfunction, or a combination of multiple factors.
Originally, Gotlib explained, his study was not designed to look at the impact of COVID-19 on brain structure. Before the pandemic, his lab had recruited a cohort of children and adolescents from around the San Francisco Bay Area to participate in a long-term study on depression during puberty – but when the pandemic hit, he could not conduct regularly-scheduled MRI scans on those youth.Once Gotlib could continue brain scans from his cohort, the study was a year behind schedule.
These findings might also have serious consequences for an entire generation of adolescents later in life, added co-author Jonas Miller. During the study, he was a postdoctoral fellow in Gotlib’s lab, and he is now an assistant professor of psychological sciences at the University of Connecticut.
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