Learn about the phase 2 PRINCE trial, led by AACR23 Opening Plenary Session chair Robert Vonderheide, in patients with PancreaticCancer parkerici
, Duration of response of patients in the efficacy population who had a partial or complete response. PFS, DOR and the corresponding 2-sided 95% confidence interval were estimated by the Kaplan-Meier method. CI = confidence interval; NE = not estimable.
Extended Data Fig. 4 A non-immunosuppressive tumor microenvironment and activated circulating CD8 T cells before treatment are associated with survival in mPDAC patients treated with nivo/chemo., Heatmap showing results of unsupervised clustering of gene expression signatures and survival status in the nivo/chemo arm. Individual patients are shown in columns and annotated by survival status at 1 year to illustrate association.
Extended Data Fig. 6 T helper signatures and proliferating CD4 T cells in the tumor associate with survival in patients receiving sotiga/chemo treatment., Heatmap showing results of unsupervised clustering of gene expression signatures and survival status in the sotiga/chemo arm. Individual patients are shown in columns and annotated by survival status at 1 year to illustrate association.
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