Study finds rhythmic gene expressions to be significantly impacted in simulated microgravity affecting astronauts long term health.
A new study aiming to understand the impact of simulated microgravity on gene expression rhythms in humans revealed that this simulated microgravity indeed disrupts gene expression in humans.
“Human gene expression varies rhythmically over the 24-hour day, and it is important to collect time series data rather than from just single time points to get a full picture of what occurs in the body when exposed to simulated microgravity,” he added. The team discovered 91 percent of these gene expressions to be impacted by the protocol with significant disruptions to the rhythmic patterns. This further affects the biological processing of the human body from protein translation, immune response, and inflammation to muscle function.
“Space travel was once thought to be unachievable; however, the growth of the space industry means it is now a real possibility,” expressed Senior author Derk-Jan Dijk, professor of sleep and physiology and director of the Surrey Sleep Research Centre.
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