Scientists make stunning discovery, find new protein activity in telomeres PNASNews
Scientist first identified telomeres about 80 years ago, and because of their monotonous sequence, the established dogma in the field held that telomeres could not encode for any proteins, let alone ones with potentIn 2011 a group in Florida working on an inherited form of ALS reported that the culprit was an RNA molecule containing a six-base repeat which by a novel mechanism could generate a series of toxic proteins consisting of two amino acids repeating one after the other.
Al-Turki and Griffith then chemically synthesized VR and GL to examine their properties using powerful electron and confocal microscopes along with state-of-the-art biological methods, revealing that the VRis present in elevated amounts in some human cancer cells, as well as cells from patients suffering from diseases resulting from defective telomeres.
"We think it's possible that as we age, the amount of VR and GL in our blood will steadily rise, potentially providing a new biomarker for
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