The Fountain of Youth may be the stuff of legend, but the search for a way to stop humans from aging is happening as we speak—inside the laboratory.
While the Fountain of Youth is the stuff of legend, the search for a way to stop humans from aging is happening as we speak—inside the laboratory.on April 8, scientists at Babraham Institute in the U.K. managed to de-age the skin cells of a 53-year-old woman by 30 years in a petri dish. Looking at age-related biological changes in the DNA, these genetically-modified younger cells appeared and behaved as any 23-year-old skin cell should.
Most rejuvenation or regeneration research makes use of human stem cells, which have the unique ability to develop into any other type of cell our body needs, such as muscle and brain cells. Stem cells can also renew themselves over time and serve as an internal repair system, replacing lost or damaged cells during a person’s lifetime. But stem cells are quite difficult to produce in the lab—and are often rejected by the body when used in different types of therapies.
“I remember the day I got the results back and I didn't quite believe that some of the cells were 30 years younger than they were supposed to be,” Dilgeet Gill, a biomedical researcher at Babraham Institute and lead author of the study,Young fibroblasts in the first image. The next two images are after 10 days, right with treatment. The last two images are after 13 days, right with treatment. Red shows collagen production which has been restored.
Dr. Johann Gudjonsson, a dermatologist who studies inflammatory skin conditions at The University of Michigan and wasn't involved in the study, is also skeptical of the experiment.
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