“There remains insufficient evidence to provide guidance on the use of cannabinoids for treating mental disorders within a regulatory framework,” the study says.
. She added: “Until evidence from randomized controlled trials is available, clinical guidelines cannot be drawn up around their use in mental health disorders.”
The 83 studies included in the review were conducted between 1980 and 2018 and cover 3,067 people. Most of the studies focused on treating depression and anxiety with cannabinoids. Only three ADHD studies were included in the review. The researchers found that use of pharmaceutical THC did not significantly affect any of the primary outcomes associated with the mental disorders, but it increased the number the people who reported negative side effects, according to several analyzed studies.
The same product, according to one of the analyzed studies, worsened the symptoms of psychosis. In other studies, it improved anxiety symptoms, though the researchers said this was “very low-quality evidence.”“There remains insufficient evidence to provide guidance on the use of cannabinoids for treating mental disorders within a regulatory framework,” the review concludes. “Further high-quality studies directly examining the effect of cannabinoids on treating mental disorders are needed.
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