Safer Blood Thinners: Innovative Treatment Prevents Blood Clots Without Increased Bleeding Risk

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Safer Blood Thinners: Innovative Treatment Prevents Blood Clots Without Increased Bleeding Risk
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Researchers have developed a new compound, MPI 8, that offers a safer and more effective blood thinner by targeting a non-essential molecule in blood clotting. The drug has shown promise in animal models without increased bleeding risk, and its design platform may allow for additional similar compou

By combining their expertise in blood clotting systems and chemical synthesis, the researchers have designed a new compound called MPI 8 that offers the potential to prevent blood clots without any increased risk of bleeding—a common side effect of existing blood thinners.

Blood clots are a serious health concern affecting millions of people around the world. When left untreated, they can lead to life-threatening conditions such as deep vein thrombosis, heart attack, pulmonary embolism, and stroke. UBC and Michigan researchers took an innovative approach to instead target polyphosphate, a molecule involved in blood clotting that accelerates the process but is not essential for it.

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