According to researchers, a groundbreaking electromagnetic device has set a new benchmark for precision in the field of mechanobiology. This device, which enables accurate measurement of a variety of soft biological tissues, makes it possible to conduct mechanical tests on samples the size of human
Institute for Medical Engineering and Science has resulted in a device that relies on magnetic actuation and optical sensing, thus potentially allowing for live imaging of the tissue under an inverted microscope. This way, insights can be gained into the behavior of the tissue under mechanical forces at both a cellular and molecular level.
To directly assess the performance of their electromagnetic device, the researchers conducted a study on the biomechanics of a mouse esophagus and of its constitutive layers. The esophagus is the muscular tube connecting the throat with the stomach and it is composed of multiple tissue layers. The researchers used the device to conduct the first biomechanical investigation of each of the three individual layers of the mouse esophageal tissue.
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