Researchers Warn: Popular Sugar-Free Sweetener Linked to Higher Rates of Heart Attack and Stroke

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Researchers Warn: Popular Sugar-Free Sweetener Linked to Higher Rates of Heart Attack and Stroke
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Cleveland Clinic research showcases the need for further safety studies. New Cleveland Clinic research showed that erythritol, a popular artificial sweetener, is associated with an increased risk of heart attack and stroke. Findings were published yesterday (February 27, 2023) in the journal Nature

A recent study conducted by Cleveland Clinic found that erythritol, a commonly used artificial sweetener, is linked to higher risks of heart attack and stroke. The study’s results were published in the journal Nature Medicine.New Cleveland Clinic research showed that erythritol, a popular artificial sweetener, is associated with an increased risk of heart attack and stroke. Findings were published yesterday in the journalResearchers studied over 4,000 people in the U.S.

Artificial sweeteners, such as erythritol, are common replacements for table sugar in low-calorie, low-carbohydrate, and “keto” products. Sugar-free products containing erythritol are often recommended for people who have obesity, diabetes or metabolic syndrome and are looking for options to help manage their sugar or calorie intake. People with these conditions also are at higher risk for adverse cardiovascular events like heart attack and stroke.

Erythritol is about 70% as sweet as sugar and is produced through fermenting corn. After ingestion, erythritol is poorly metabolized by the body. Instead, it goes into the bloodstream and leaves the body mainly through urine. The human body creates low amounts of erythritol naturally, so any additional consumption can accumulate.

The authors note the importance of follow-up studies to confirm their findings in the general population. The study had several limitations, including that clinical observation studies demonstrate association and not causation.

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