Science, Space and Technology News 2024
Researchers at Weill Cornell Medicine identified a novel link between the IL-23 immune pathway and CTLA-4 in ILC3 cells, which plays a pivotal role in regulating inflammation and maintaining gut health, potentially impacting the treatment of inflammatory bowel diseases and cancer immunotherapy. Their findings could lead to more targeted therapies that balance immune response while preserving intestinal function in diseases like IBD and during cancer treatments.
The findings identify ILC3s as a critical link between potent IL-23 driven inflammatory response and checkpoints for immune regulation in the intestine. It also provides clues on how to harness this pathway to fight cancer and alleviate a serious side effect of cancer immunotherapy. They then verified this finding in patients through collaboration with Dr. Robbyn Sockolow, professor of clinical pediatrics and chief of the Division of Pediatric Gastroenterology, Hepatology and Nutrition in the Department of Pediatrics at Weill Cornell Medicine and a pediatric gastroenterologist at NewYork-Presbyterian Komansky Children’s Hospital and Center for Advanced Digestive Care.
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Previously unknown dormouse habitat identifiedBayreuth researchers have shown for the first time that the dormouse, which is strictly protected in Germany, not only uses woody structures as a habitat, but also reed beds. The study is published in the Journal of Vertebrate Biology.
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Partial skeleton of a previously unknown medium-sized theropod dinosaur found in SiberiaStudy of a partial skeleton found embedded in a rock has resulted in the discovery of a new species of dinosaur. Using a variety of technology and techniques, researchers affiliated with several institutions in the Russian Federation found that the fossil once belonged to a previously unknown dinosaur they have named Kiyacursor longipes.
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Accused Gilgo Beach killer Rex Heuermann charged with two more murders, including previously unknown victimSandra Costilla and Jessica Taylor were just added to the list of alleged Long Island serial killer victims. Here's what we know.
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Testing immune cells in the placenta may indicate the health of fetal brain immune cellsImmune activation in a pregnant woman can occur in response to metabolic diseases like obesity, infections in pregnancy, exposure to pollution and environmental toxins, or even stress and can have negative effects on fetal brain immune cells (microglia).
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Pesticides impair mobility and immune system of Brazilian native stingless bees, study showsA study conducted by Brazilian researchers affiliated with São Paulo State University (UNESP), the Federal University of São Carlos (UFSCar) and the Federal University of Viçosa (UFV) has shown how three pesticides widely used by farmers in Brazil—imidacloprid, pyraclostrobin and glyphosate—affect native stingless...
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How the immune system can cause psychosis, and tool use in ottersOn this week’s show: What happens when the body’s own immune system attacks the brain, and how otters’ use of tools expands their diet
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