To raise awareness for Alzheimers and brain awareness month this study found that PPIL4 is essential for brain angiogenesis and is implicated in intracranial aneurysms in humans
We are indebted to the patients and families who have contributed to this study. We would like to thank M. Cavanaugh for the zebrafish husbandry. Funding: This work was supported by Yale University funds and National Institutes of Health grants 4R01NS057756-10 , 1R01NS111935-01 and R01 NS109160-04 and R01 HL130246-05 .Authors and AffiliationsTanyeri Barak, A. Gulhan Ercan-Sencicek, Danielle F. Miyagishima, Octavian Henegariu, E.
Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale School of Medicine, New Haven, CT, USALaboratory of Human Genetics and Genomics, The Rockefeller University, New York, NY, USADepartment of Genetics, Washington University School of Medicine, St.
Department of Neurosurgery, Columbia University College of Physicians and Surgeons, New York, NY, USADepartment of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USAKristopher T. KahleKristopher T. Kahle
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