Oldest known sex chromosome emerged 248 million years ago in an octopus ancestor

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Oldest known sex chromosome emerged 248 million years ago in an octopus ancestor
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Stephanie Pappas is a contributing writer for Live Science, covering topics ranging from geoscience to archaeology to the human brain and behavior.

The oldest known sex chromosome in animals has been discovered, pushing back the date for the evolution of sex chromosomes to between 248 million and 455 million years ago.

For a long time, researchers weren't sure whether cephalopods, the soft-bodied mollusks that include squid and octopuses, determined their sex with chromosomes. Mollusks have a variety of ways to handle reproduction, including hermaphroditism or sequential hermaphroditism, in which individuals swap sexes over time.

This was a clue that chromosome 17 might have something to do with sex differences. To confirm, the team sequenced four more octopuses, two male and two female, and confirmed that females have just one copy of chromosome 17, while males have two. Thus, they represent the octopus sex chromosomes not as XY and XX as in humans, but as ZZ and Z0.

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