The majority of antidepressants prescribed for chronicpain lack sufficient evidence of efficacy and safety, results of a large Cochrane review show.
Duloxetine was consistently the highest-ranked antidepressant and was equally effective for fibromyalgia, musculoskeletal, and neuropathic pain conditions, with moderate- to high-certainty evidence, the researchers found.
Milnacipran also appeared to be effective at reducing pain, but"we are not as confident in this result as duloxetine because there were fewer studies with fewer people," Birkinshaw noted."Aside from duloxetine and milnacipran, we do not have confidence in the results from any other antidepressant included in this review. This includes amitriptyline, even though it's the most common antidepressant used clinically," Birkinshaw added.
Indonesia Berita Terbaru, Indonesia Berita utama
Similar News:Anda juga dapat membaca berita serupa dengan ini yang kami kumpulkan dari sumber berita lain.
Tesla Model 3 Is One Of The Most Reliable Cars In Germany: ADAC StudyThe American EV ranks among the most reliable cars in ADAC's reliability index which analyzes how many breakdowns per 1,000 vehicles occurred for a specific model.
Baca lebih lajut »
Reliable broadband is a necessity for all Americans.RepRickAllen: 'To close the digital divide and further America’s leadership in next-generation broadband and wireless networks, we need effective reforms to accelerate the build out of high-speed connections.' Infrastructure2023 sponsored
Baca lebih lajut »
How Medical Records Can Close the Information Gap in Patient CareIn dealing with many cases, doctors lack comparative real-time evidence and are forced to make decisions in spite of unknown variables that can dramatically alter outcomes. Such evidence gaps happen every day, particularly for patients with multiple conditions, complex medical histories, and diverse ethnic backgrounds. Breakthroughs in academic research, including a major project at Stanford University School of Medicine, have led to technological innovations that allow clinicians to generate on-demand evidence drawn from research data and anonymized medical records, bridging the evidence gap so doctors can make informed decisions that improve outcomes.
Baca lebih lajut »
Evidence Suggests Brazil's Soccer Match-Fixing Scandal Could Be International IssueThe lead investigator of Brazil’s sprawling match-fixing scandal said he has uncovered potential evidence of wrongdoing by players in other countries, and he hopes foreign authorities will use his team’s findings to start probes of their own.
Baca lebih lajut »
First Evidence of Dark Stars?Astrophysicists propose the universe's first stars, heated by dark matter, were supermassive 'DarkStars' 🌟 Evidence of their existence may have been found by the James Webb Space Telescope 🔭✨
Baca lebih lajut »
New evidence shows OnlyFans model Courtney Clenney acted in self-defense, lawyer claimsThe lawyers for OnlyFans model Courtney Clenney — who allegedly killed her boyfriend during a blowup in their luxury Miami apartment – have claimed they have new evidence she acted in self-de…
Baca lebih lajut »