The primary reasons finding a cure for cancer has proved so difficult are that traditional cancer treatment strategies also affect normal cells. This often leads to debilitating side effects.
Cancer Antibodies Inc. presented the results of a research study of their new platform which facilitates rapidly finding: multiple cancer-specific sites simultaneously. The method is based on the fact that if you introduce a human cell into a non-human vertebrate, the animal’s immune system will recognize the human cells as foreign and make antibodies against them. If antibodies are found that bind only to cancer cells, they can be used to create targeted therapies that do not harm normal cells.
The finding of these new targets and their corresponding antibodies unlock the reality of precisely targeted treatments that do not harm normal cells. Also, as the cancer grows and spreads, the tumor cell DNA mutates further making molecular targeted therapies ineffective. The cancer-specific ADCs were tested on breast cancer and normal breast cells. The cancer and normal cells were taken from the same individual and the same tissue type. The results demonstrated that the cancer cells were killed while the normal cells remained unscathed.
cancer cells that are of a similar type but from different individuals can share the same cancer-specific antigens .Cancer Antibodies Inc.’s unique ability to find cancer-specific antigens, and create antibodies and ADCs that target these sites has huge implications for the development of effective therapies that are tailored for each individual’s cancer as well as agents that work across individuals that have the same type of cancer and even individuals that have different types of cancer.
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