Newly published data indicates that widely available medications for chronic lymphocytic leukemia have steadily improved overall survival rates over most of the past three decades. CLL OncTwitter
While cutting-edge treatments such as CAR T-cell therapies, clinical trials, and costly transplants for chronic lymphocytic leukemia are not accessible to all 200,000+ people living with the disease nationwide, newly published data indicate that widely available medications for this most common of adult leukemias have steadily improved overall survival rates over most of the past 3 decades.
Although the study was not designed to specify which treatments were disseminated among patients or to estimate the impact of a specific drug, there were only six new drugs approved for CLL from 1991 to 2010. In contrast, between 2011 and 2018, 11 new CLL drugs ) ushered in a period of more rapid annual decreases in mortality.
New TKIs not only decrease mortality, but also have fewer side effects than earlier cytotoxic therapies, do not require inpatient treatment, and are available to all patients on Medicare and Medicaid. Even though TKIs increase overall survival in patients with CLL, they are not curative and require lifelong treatment.
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