Single ulcers, anal lesions, and mouth sores are all unique symptoms of the current monkeypox outbreak.
The study"importantly reinforces our current understanding that the overwhelming majority of cases have been sexually associated, predominantly in men who have sex with men," said Jeffrey Klausner, MD, PhD, an infectious disease specialist at the Keck School of Medicine at the University of Southern California, Los Angeles, in an interview withHe was not involved with the research.
The fact that most lesions are present in the genital and anal region — which is unique to this outbreak — points to transmission of the infection during intimate contact, he noted. Still, there is not enough evidence to suggest that monkeypox is spread through sexual transmission. While most semen samples in the study tested positive for monkeypox viral DNA, it is not known whether there is enough virus present to cause transmission, Thornhill said. He noted that more research is needed.
Klausner also emphasized the importance of developing new tests to diagnose monkeypox earlier to prevent spread. The lab test for monkeypox requires a swab from a lesion, but this study showed that most patients had notable symptoms prior to developing the standard rash or lesions, he said. Reliable tests using saliva or throat swabs could help detect infections faster, he noted.
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