Women who become pregnant during IVF from previously frozen embryos have a significantly higher chance of developing hypertensive disorders such as preeclampsia, researchers have found.
reproductive technology
Petersen and his colleagues compared maternal complications in sibling pregnancies. Women who became pregnant following the transfer of a frozen embryo were 74% more likely to develop a hypertensive disorder than women who became pregnant following natural conception . The difference was even higher with respect to sibling births: women who became pregnant using frozen embryos were 102% more likely than women who became pregnant using natural conception to develop a hypertensive disorder .
"When we find that the association between frozen embryo transfer and hypertensive disorders in pregnancy persists in sibling comparisons, we believe we have strong indications that treatment factors might in fact contribute to the higher risk," Petersen toldWomen in the study who became pregnant after natural conception had a 4.3% chance of developing hypertensive disorders.
"The vast majority of IVF pregnancies, including frozen embryo transfer, are healthy and uncomplicated, and both short- and long-term outcomes for both the mother and the children are very reassuring," Petersen said.
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