Mayo Clinic Reveals Data on Rebound COVID-19 Symptoms After Paxlovid Treatment

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Mayo Clinic Reveals Data on Rebound COVID-19 Symptoms After Paxlovid Treatment
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Mayo Clinic researchers studied the outcomes of treating high-risk patients for COVID-19 with a five-day oral regimen of nirmatrelvir and ritonavir, which are together marketed as Paxlovid. Out of 483 high-risk patients, only a handful developed COVID rebound symptoms, and the scientists say more re

In a Mayo Clinic study published in the journal Clinical Infectious Diseases, only 4 people out of 483 high-risk patients treated with Paxlovid developed COVID-19 rebound symptoms.with a five-day oral regimen of nirmatrelvir and ritonavir, which are together marketed as Paxlovid. Out of 483 high-risk patients, only a handful developed COVID rebound symptoms, and the scientists say more research is needed to determine why.

Most of the patients in the study had been vaccinated, and many had received booster vaccinations. The median age was 63. While these patients were high-risk for COVID-19, none was immunocompromised. Only two patients were admitted to the hospital, and it was for reasons other than COVID.A 75-year-old man with coronary artery disease who had increased cough and muscle aches 19 days after treatment.

A 40-year-old woman with obesity, hypertension, and kidney disease who developed fatigue and sore throat six days after treatment.

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