Massive trial shows COVID rapid tests excel at detecting silent cases

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Massive trial shows COVID rapid tests excel at detecting silent cases
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In a trial in 73 workplaces, the tests detected hundreds of people with asymptomatic COVID-19 and generated an extremely low false-positive rate.

Rapid COVID-19 testing in Canadian workplaces yielded only 75 confirmed false-positive results out of nearly 322,000 administered tests. Credit: Artur Widak/NurPhoto via Getty

A large-scale testing campaign in Canadian workplaces shows that the regular use of rapid antigen tests is highly effective at ferreting out asymptomatic SARS-CoV-2 infectionsRapid antigen tests identify proteins on the virus’s surface and are faster and cheaper than more-sensitive polymerase chain reaction tests, which can pinpoint tiny amounts of the virus by detecting its RNA.

From January 2021 to June 2021, nearly 322,000 rapid tests were conducted at 73 workplaces. Testing yielded 604 positives; 473 of those were confirmed by PCR to be true positives. Only about one in 4,300 rapid-test results was confirmed by PCR as a false positive, which the authors note was not enough to disrupt workplace operations.

Of the 116 workplace-testing organizers who responded to a survey, 99% said they were either satisfied or very satisfied with the programme.

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