Malaria-driven adaptation of MHC class I in wild bonobo populations - Nature Communications

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Malaria-driven adaptation of MHC class I in wild bonobo populations - Nature Communications
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Malariainfection harms wild African apes, study shows wustl NatureComms

alleles in bonobos at TL2-E. Although we sampled only seven bonobos at other locations east of the Lomami, all seven were homozygous for B07 alleles, suggesting that the TL2-E population is typical of others in the eastern region. From comparisons of mtDNA haplotypes it has been suggested that western bonobos arose about 0.26–0.

These bonobos have regained, but presumably only after they migrated to this location within range of the mosquitoes that bite bonobos at TL2-E. At TL2-W the frequency of B07 alleles has climbed to about 50% and, strikingly, most of these B07 alleles are identical to those found at low frequencies in other western populations, but different from those found at high frequencies at TL2-E.

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