Science, Space and Technology News 2024
Researchers at the University of Connecticut have developed a promising treatment that not only extends the lifespan of mice but also enhances their physical function throughout life. This study tracked health metrics such as grip strength and walking speed from an advanced age until death, showing that treated mice were healthier and less frail than untreated ones in their final days. The results suggest potential for extending healthy human lifespans by up to 10 years.
Researchers found that removing certain inflammation-causing cells from mice every month, starting in their middle age, not only extended their lifespans but also improved their heart health and overall physical function throughout their lives. This method shows promise for extending the period of good health as mice age, potentially pointing to new aging treatments for humans.
Excitingly, they found that even though the treated mice were older at the time of death, their physical function and overall frailty were better than those of the controls during their last stage of life. The researchers used two groups of mice. One group received monthly treatments to remove highly inflammatory cells from their tissues; the control group did not. ‘Highly inflammatory cells’ were defined as those actively expressing a specific gene called p21.
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