Long-term use of oral hormone therapy may be associated with a small increased risk of Alzheimer’s disease in postmenopausal women, researchers report.
A woman, suffering from Alzheimer's desease, walks in a corridor on March 18, 2011 in a retirement house in Angervilliers, eastern France.Get breaking news alerts and special reports. The news and stories that matter, delivered weekday mornings.Long-term use of oral hormone therapy may be associated with a small increased risk of Alzheimer’s disease in postmenopausal women, researchers reported Wednesday.
“It prompted us to do research on Alzheimer’s disease to see if the same results persisted, but it doesn’t look like hormonal therapy provided a protective effect on Alzheimer’s,” said lead author Dr. Tomi Mikkola, supervisor for the obstetrics and gynecology doctoral program in clinical research at the University of Helinski.
The specific reasons behind this increased risk are elusive, but biological differences between Alzheimer’s and vascular dementia may be one reason why, Mikkola says. “Alzheimer’s is a completely different type of disease, we don’t know the mechanism behind the disease. What we know is that the disease has started decades before we see symptoms of memory loss,” said Mikkola.Alzheimer’s disease is the sixth-leading cause of death in the United States. Nearly 6 million Americans have been diagnosed with Alzheimer’s — two-thirds are women — including 200,000 under the age of 65.
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