Clinicians need to learn how to diagnose and manage cannabis allergies:
Lorraine L. Janeczko, MPHAs medicinal and recreational cannabis become legal and more popular in more places, clinicians need to learn how to diagnose and manage cannabis allergies, an internationalAllergic reactions to cannabis include rhinitis, conjunctivitis, asthma, skin reactions, and anaphylaxis to hemp seed. Exposure can come from smoking, eating, inhaling cannabis pollen or smoke, and contact with skin, and includes occupational allergies.
No commercial extracts are available for clinical testing, so unstandardized prick-prick tests with cannabis buds, leaves, or seeds may be the only option, if available. But cross-reactivity in patients sensitive to pollen and plant foods may make positive prick-prick results clinically insignificant.
The paper on cannabis allergy is an early step. To help educate healthcare professionals and foster future research about cannabis allergies, members of the American College of Asthma Allergy and Immunology , the European Academy of Allergy and Clinical Immunology , and the Canadian Society of Allergy and Clinical Immunology have formed the Cannabis Allergy Interest Group .
"Allergies to plant extracts from plants such as cannabis can be avoided, if the main goal is to deliver an active ingredient such as THC or related compounds," Lo, who was not involved in developing the consensus document, explained."In that case, a more highly purified — or even better, a synthetic version — would be used, so the protein that is the target of the allergy would be absent.
"That's why you see so many food labels saying the food was prepared in a factory where nuts or peanuts are processed. Allergens can be detected by the immune system, and potentially trigger anaphylaxis, at extremely low concentrations.
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