Hippocampal astrocytes encode reward location - Nature

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Hippocampal astrocytes encode reward location - Nature
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Nature research paper: Hippocampal astrocytes encode reward location

Extended Data Fig. 3 Astrocytic Activity Does Not Ramp Towards Rewarding Location in a New Environment.. The correlation between location and astrocytic activity in repeated active ROIs was significantly higher in the familiar environment compared to the new one . The repeated active ROI pairs that had significant mutual information in each environment of the mouse shown in Fig..

The mean normalized number of concurrent events as a function of location in the familiar environment and in the new environment for all active ROIs, not just the repeated ones, in the 7 mice shown in Fig.. The ramping of astrocytic activity is significantly larger in the familiar environment than in the new environment . Two mice were imaged for the third time in the familiar environment after the exposure to the new environment.

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