They way these medications are designed matters.
Why don’t some monoclonal antibody treatments work well against Omicron?
As a result, “it is not expected that these products will have any meaningful effect on those with the Omicron variant,” says infectious disease expert Amesh A. Adalja, M.D., a senior scholar at the Johns Hopkins Center for Health Security. “The company felt that binding site was less likely to be altered [during mutations of the virus] and apparently they were right,” Dr. Russo says.This is a little tricky. If you qualify for monoclonal antibody treatment and you know that you have the Omicron variant of COVID-19, the Eli Lilly and Regeneron treatments are unlikely to do anything. In fact, it’s likely that they “are not even really going to be available anymore” very shortly, Dr.
"A lot depends on exactly where in the country you are and how much information the local doctors have about the local prevalence of," says William Schaffner, M.D., an infectious disease specialist and professor at the Vanderbilt University School of Medicine."In Tennessee, for example, cases are still mostly fueled by Delta but obviously Omicron is coming on strong.
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