“After long bed rest, humans are just not jumping up and down and climbing mountains. But that’s what these [squirrels] have to do.”
Gut microbes give some squirrels a helping hand to stay strong during hibernation. The microorganisms appear toUnderstanding how squirrels keep their muscle over the winter could offer a small clue to figuring out how to stave off muscle loss for people who are malnourished or have muscle-wasting diseases, the scientists say.
“After long bed rest, humans are just not jumping up and down and climbing mountains,” says study coauthor Hannah Carey, a hibernation physiologist at the University of Wisconsin-Madison. “But that’s what these [squirrels] have to do.” Muscle breakdown from inactivity or starvation releases compounds made of nitrogen — a crucial element found in muscle building blocks called amino acids. Too much nitrogen can be toxic, so the body normally eliminates the excess through urine in a compound called urea.
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