Cancer doctors and researchers “don’t use words like ‘cure’ lightly or easily.” But with two patients remaining cancer-free for more than a decade, the therapy has performed “beyond our wildest expectations.”
In 2010, two blood cancer patients received an experimental immunotherapy, and their cancers went into remission. Ten years later, theCalifornia resident Doug Olsen was one of the patients. “From a patient’s viewpoint, when you’re told you’re pretty much out of options, the important thing is always to maintain hope. And certainly, I hoped this was going to work,” Olsen said at a February 1 news briefing.
Olsen and the other patient had chronic lymphocytic leukemia. Both responded well to initial treatment. But it was unclear how long the modified cells would stick around, preventing the cancer’s return. Cancer doctors and researchers “don’t use words like ‘cure’ lightly or easily,” said oncologist and study coauthor David Porter of the University of Pennsylvania at the briefing. But with both patients remaining cancer-free for more than a decade, he said, the therapy has performed “beyond our wildest expectations.”
The biggest disappointment is that the immunotherapy doesn’t work for everyone, Porter added. Some people don’t respond to the treatment. Others can develop . But researchers are “starting to learn the mechanism of why and how it works, so that we can start to get at how to make it work for more people,” he said.
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