Alcohol use disorder, also known as alcoholism, affects roughly 30 million people 12-years-old and older in the U.S. alone.
. The study, which involved nonhuman primates, showed that the treatment could drastically reduce alcohol use in chronic heavy drinkers.
The brains of animals that chronically binge drink typically struggle to produce dopamine, the feel-good reward chemical produced by the body. In healthy bodies, even low doses of alcohol releases dopamine. However, those with alcohol use disorder require more and more alcohol in order to feel the same effects.
The trials involved eight rhesus macaque monkeys that heavily drank water-diluted ethanol. Four of the monkeys were given the treatment while the other half stood as the control. The study’s authors observed that alcohol consumption dropped by more than 90 percent amongst the gene therapy group when compared to a control group.
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