As experimental drugs to treat NASH continue to dash themselves on the shoals of the federal regulatory system, clinicians should know that at least one effective therapy exists.
"Just like diabetes, NAFLD is a silent disease that is progressing,' said Shubrook, who is also a co-author ofHe recommended using the FIB-4 assessment — an easy calculation that comprises age, levels of the liver enzymes aspartate transaminase and alanine aminotransferase, and platelet counts — to determine patients most at risk for NASH and eventually cirrhosis.
Those in the lowest risk groups should also be counseled on how to reduce weight. But unless their liver shows signs of worsening, people in this group would always remain in the care of a primary care clinician and not a hepatologist. And clinicians should always pay attention to how they communicate with patients, regardless of the severity of their case, Cryer advised:
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