FDA advisers recommend updating COVID booster shots to match newer variants

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FDA advisers recommend updating COVID booster shots to match newer variants
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Advisers to the U.S. government are recommending that COVID-19 booster shots used this fall be modified to better match more recent variants of the coronavirus.

At least some U.S. adults may get updated COVID-19 shots this fall, as government advisers voted Tuesday that it's time to tweak booster doses to better match the most recent virus variants.

"We are going to be behind the eight-ball if we wait longer," said one adviser, Dr. Mark Sawyer of the University of California, San Diego. It's not clear who would be offered a tweaked booster - they might be urged only for older adults or those at high risk from the virus. But the FDA is expected to decide on the recipe change within days and then Pfizer and Moderna will have to seek authorization for the appropriately updated doses, time for health authorities to settle on a fall strategy.

Both companies found the tweaked shots also offered some cross-protection against those worrisome BA.4 and BA.5 mutants, too, but not nearly as much. Further complicating the decision is that only half of vaccinated Americans have received that all-important first booster. And while the CDC says protection against hospitalization has slipped some for older adults, a second booster that's recommended for people 50 and older seems to restore it. But only a quarter of those eligible for the additional booster have gotten one.

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