Electrical stimulation of cervical spinal circuits facilitates arm & hand movements in two participants with moderate & severe chronic post-stroke hemiparesis. MCapogrosso PittNeurosurg
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.sagittal, coronal, and axial T1- weighted MRI 2D projections for SCS01 and SCS02. The segmented lesion is shown in red for both participants. R indicates the Right hemisphere.
communication protocol over a virtual serial port. The microcontroller’s firmware delivered pulse triggers and amplitude control signals to the stimulator as well as an 8 bit parallel channel selection signal to the multiplexer in order to control pulse timing, amplitude, and output channel. Current was delivered from the stimulator through the multiplexer and ultimately to the selected electrode on the implanted spinal array.
The microcontroller firmware allowed for pseudo-synchronous stimulation across multiple channels by interleaving pulses on all active channels. A delay of at least 1 ms between each pulse allowed enough time for the multiplexer to fully switch channels. The same pattern of pulses was delivered every period as defined by the stimulation frequency.
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