Eli Lilly expects FDA decision on Alzheimer's treatment donanemab by the end of the year

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Eli Lilly expects FDA decision on Alzheimer's treatment donanemab by the end of the year
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Eli Lilly says it has applied for full FDA approval of its Alzheimer’s treatment, donanemab, and expects the agency to make a decision by the end of the year. CEO David Ricks joins SquawkStreet to discuss.

Almost half of patients – 47% – who received donanemab showed no disease progression a year after treatment began, according to the final trial results. That compares with 29% for those who did not receive the drug.

"The results illustrate that initiating treatment as early as possible enables the possibility of a bigger beneficial effect, but also that there is potential for slowing of disease progression even when treatment is started later in the disease progression," said Maria Carrillo, chief science officer of the Alzheimer's Association, in a statement.

Donanemab cleared amyloid plaque at six months in 34% of patients who had intermediate levels of a protein called tau, which can become toxic and kill neurons.

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